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Left Ventricular Mass Index
The mass of the left ventricular myocardium normalised to body surface area. Used to diagnose and grade left-ventricular hypertrophy.
LVMI is calculated by indexing LV mass (derived from LV wall thickness and chamber dimensions) to body surface area (BSA) in g/m². Reference ranges are sex-specific: ≤95 g/m² in women and ≤115 g/m² in men (ASE 2015).
Elevated LVMI is a strong independent predictor of cardiovascular events, including heart failure, stroke, and sudden cardiac death. It is also one of the structural pillars of HFpEF diagnosis.
Automated LV mass derivation from AI-segmented echocardiograms reduces the impact of inter-observer disagreement on wall thickness, which historically dominates the LVMI measurement error.