Automate Your Echo Core Lab
One algorithm reads every study. Fully automated analysis. A structured draft report typically within two minutes of DICOM upload.
Echocardiography Remains One of the Most Variable Imaging Modalities in Clinical Trials
Manual core labs introduce compounding risks that grow with every additional site, patient, and timepoint.
Measurements shift with every reader, creating inconsistent data across sites and timepoints.
Manual workflows make it difficult to enforce measurement protocols uniformly across labs.
Throughput depends on specialist availability, not trial demand.
Every additional site multiplies operational complexity.
Qualified echo readers are a finite, expensive resource. Demand outpaces supply.
From Manual Core Lab to Fully Automated
See how Us2.ai compares to current approaches.
Manual Core Lab
- Manual frame selection & measurement
- Reader-to-reader variability between experts
- Many clicks and minutes of manual measurement per study
- Specialist-dependent throughput
- Ad-hoc QA, no audit trail
- Manual eligibility review post-upload
AI-Assisted Analysis
- AI suggests measurements
- Reduced variability
- Still requires click-by-click approval
- Partial automation only
- No integrated workflow management
- No eligibility or outlier automation
Automated Core Lab
- Zero-click AI measurement generation
- Less variability than between expert readers
- Full report typically within 2 minutes
- Scales without specialist headcount
- Structured 4-stage QA with audit log
- Real-time eligibility & outlier detection
From DICOM Upload to Clean Data, Automatically
Us2.ai slots into your existing core lab infrastructure and processes studies end-to-end.
DICOMs uploaded via link or batch integration
Protocol criteria verified instantly at upload
Full echo report typically within 2 minutes, zero clicks
4-stage review with full audit trail
Clean CSV and statistical outputs to sponsor or CRO
Standard DICOM echo studies, not tied to a single scanner manufacturer. Single or bulk upload. Retrospective and prospective designs.
Cloud or on-premise. Automated view classification, measurement, outlier detection, and eligibility screening.
Structured CSV and report data. Audit-logged, anonymised, and ready for biostatistics and regulatory submission.
Choose Your Level of Automation
The AI Engine
Us2.ai Software & License
On-premise or CloudAdd AI-powered echo analysis to your existing workflow. Protocol-matched structured outputs, no infrastructure overhaul.
- Automated 2D, Doppler & Strain
- Protocol-matched CSV extraction
- On-premise or AWS cloud
- Study review & editing interface
- Guideline-compliant, zero clicks
Power Up Your Core Lab
AI analysis + workflow management
Cloud · ConfigurableAI echo analysis with automated workflow, eligibility checks, structured QA, and audit logging in one platform.
- Eligibility screening at upload
- 4-stage structured QA workflow
- Integrated query system
- Outlier detection & flagging
- Role-based access & multisite
- Configurable measurement display
Next Gen Core Lab
Full end-to-end automation suite
Full Automation SuiteComplete Cloud Lab with end-to-end trial management and real-time prospective upload for Phase I–IV studies.
- All Option 2 capabilities
- Prospective upload at point-of-echo
- Configurable workflow protocol
- Longitudinal analysis & tracking
- Bulk retrospective data upload
- Real-time trial monitoring
- Anonymisation & audit traceability
Used in the HELIOS-B Cardiovascular Clinical Trial
Us2.ai software supported echocardiographic analysis in HELIOS-B, a large Phase III multicenter trial evaluating vutrisiran in patients with ATTR cardiomyopathy.
Effects of Vutrisiran on Cardiac Function and Outcomes in Patients With Transthyretin Amyloidosis With Cardiomyopathy
"Echocardiographic measurements were performed using commercially available software (US2ai) in accordance with American Society of Echocardiography guidelines." Study Procedures and Echocardiographic Methods, HELIOS-B
Ready to Get Started?
Join the clinical teams already running faster, cleaner, and more consistent trials with Us2.ai.
Talk to Our Core Lab Team
Tell us about your trial and we'll walk you through the right Us2.ai solution. We typically respond within one business day.
- AI Engine software licensing
- Cloud Lab implementation & configuration
- Trial protocol alignment
- Site training & onboarding support
Thank you for your interest. Our core lab team will review your details and get back to you within one business day.