Your AI Echo Copilot™
AI Echocardiography, From First Frame to Final Report
For echo labs and cardiology departments: every study analyzed automatically, with measurements and guideline-based conclusions back as one complete report for the clinician to review.
One routine echo study 6 areas measured and reported
- Heart Failure
- Cardiac Amyloidosis
- Aortic Stenosis
- Pulmonary Hypertension
- Strain (GLS)
- Stress Echocardiography
Us2.v2 is FDA cleared and CE marked for automated measurement, and its reports add guideline-based conclusions for the clinician to review. The amyloidosis module, Us2.ca, is cleared separately. See what each market's labeling includes.
Not One Measurement. The Whole Report.
Us2.ai returns the end-to-end report in one zero-click pass: guideline measurements, diastolic and valvular assessment, and guideline-based conclusions for the clinician to review, rather than one measurement such as strain or ejection fraction.
And it runs on the scanners you already own, vendor-neutral across GE, Philips, Siemens, Canon and handheld POCUS.
See what a full report contains- Guideline measurements
- Diastolic function
- Valvular assessment
- Chamber quantification
- Strain (GLS)
- Guideline-based conclusions
AI-Powered Cardiac Amyloidosis Detection
Cardiac amyloidosis is one of the most under-diagnosed conditions in cardiology. Us2.ca, a deep-learning model that reads the apical four-chamber clip, flags studies suggestive of cardiac amyloidosis inside the same automated, guideline-based measurement and report. FDA cleared and CE marked.
Learn more about our approach →Us2.ca is FDA cleared (K250151) for adults with increased left ventricular wall thickness, and CE marked. It supports, and does not replace, the clinician's diagnosis. See what each market's labeling includes.
Measurable Impact, Backed by Evidence
Peer-reviewed studies and clinical deployments show significant efficiency gains across echo labs.
“Well, AI will not replace a physician, but a physician using AI will replace a physician not using AI!”
Trusted by Healthcare Professionals Worldwide
Cardiac amyloidosis remains a frequently under-diagnosed condition with significant prognostic implications. Us2.ai's AI-based pattern recognition model, applied to a standard apical four-chamber view, provides a validated and scalable solution to support early detection and enhance clinical decision-making within routine echocardiographic practice.
As labeled, Us2.ca is for adults with an IVSd or LVPWd of 12 mm or more, supports the clinician's diagnosis and does not replace it. Population screening is a research use. Intended use
Us2.ai's platform already provides powerful automated measurements that support the detection of cardiac amyloidosis. But this new deep learning approach moves beyond standard measurement workflows by enabling fast, fully automated detection of amyloidosis from a single echo view. By simplifying image requirements while maintaining diagnostic accuracy, it has the potential to expand the role of echocardiography as an accessible, practical screening tool for earlier identification of patients with this life threatening yet treatable disease.
As labeled, Us2.ca is for adults with an IVSd or LVPWd of 12 mm or more, supports the clinician's diagnosis and does not replace it. Population screening is a research use. Intended use
From my personal experience, I have felt very fortunate to be able to use Us2.ai, a remarkable platform... I am truly amazed with its speed, overall accuracy and ease.
What we found is that the AI workflow saves, on average, 10 to 12 minutes per study, for a total savings of about 33% per study, which was pretty remarkable.
AI provides a consistent 'gold standard' that can be uniformly applied to all examinations, significantly reducing variability between sonographers.
I can't take my eyes off those images, and I can't believe I could get them with ZERO CLICKS!
AI can significantly shorten diagnosis time from 35 to 40 minutes down to about 10 minutes. This innovation … eases the workload for medical staff.
Thanks to the AI analysis, we immediately receive objective measurements, allowing us to make decisions faster and more consistently. That is a win-win for both the patient and the healthcare provider.
AI supports the process, but never replaces the medical judgement of the healthcare professional.
You should see it as a system that thinks alongside us and supports us in speeding up the analysis.
It is probably the most impressive tool I have seen in my career!
Something we found is the consistency that Us2.ai brings to the table, and with consistency [...] this is bringing imaging more so from a subjective modality to an objective modality, which can open a lot of doors when it comes to research, allowing us to find out new information of the heart which we didn't have before.
The US2 software could enable the use of echocardiography in screening or as a procedure at an accelerated pace and in a cost-effective manner.
Us2.ai is cleared for automated measurement with guideline-based conclusions for clinician review. Screening is a research use. Intended use
We are proud to partner with Us2.ai to enhance and complement our comprehensive AI platform, tailoring it to cardiovascular needs, so that cardiologists and care teams can provide optimal care to more patients most efficiently.
Our partnership with Us2.ai allows our health system partners to further expand the clinical value of AI to cardiac care. Health systems cannot work with thousands of AI point solutions for each service line. Our aiOS allows health systems to think strategically about AI and build an end-to-end intelligence layer across the health system.
At Advara HeartCare we are committed to improving Australia's Heart Health. Whilst our clinical teams remain the focus (or at the heart) of our patients' care, partnering with US2Ai we are excited to investigate how AI can enhance our diagnostic capabilities and optimize the experience and clinical outcomes for our patients.
Built for Everyone Who Touches an Echo
Six roles, one automated report. Pick the one that sounds like your week.
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Cardiologists
Guideline-directed structured reporting with editable AI output, validated against expert readers.
See the clinical evidence -
Sonographers
No frame selection, no manual tracing. Measurements arrive with the study.
See the workflow impact -
Hospital IT & security
Cloud or on-premise, air-gap compatible, ISO 27001 and SOC 2 Type II.
Review deployment & security -
Core labs & CROs
Reproducible, blinded, high-throughput reads with a full audit trail.
See core lab solutions -
Health systems
Throughput, capacity and reporting turnaround, modeled on your own volumes.
Estimate your ROI -
Partners & distributors
Vendor-neutral integration with the scanners and PACS your customers already run.
See partnerships
From Echo Scan to Structured Report, Automatically
Us2.ai connects to your ultrasound devices and PACS, processes echocardiograms (cardiac ultrasound studies) in real time, and delivers standardized, clinician-ready reports.
Zero-Click Analysis
No frame selection, no manual annotations. Studies are processed automatically from DICOM upload to final report. No additional clicks required.
Results During the Exam
Measurements are generated while the exam is under way, and a structured draft report is typically ready within two minutes of upload.
Fits Your Infrastructure
Cloud or on-premise. Reads DICOM from GE, Philips, Siemens, Canon, and handheld POCUS devices, and connects to PACS, CVIS, or EMR. Deploy without changing your existing clinical workflow.
Us2.ai works with industry partners, including Fujifilm, GE HealthCare, Canon Medical Systems, Microsoft, Viz.ai and Merge, and with academic collaborators, including Duke University and Brigham and Women's Hospital.
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Academic collaborator Where We Operate, and How It Gets Paid For
In the US the echo itself is billed under existing codes: CPT for outpatient, DRG for inpatient. Coverage and codes differ everywhere else.
Reimbursement in your marketModel the payback for your own lab: study volume, staffing and reporting time.
Estimate your ROICloud or On-Premise, the Same Four Milestones
Works with your existing PACS, CVIS, and EMR via standard DICOM routing. No rip-and-replace. Most of the elapsed time on either path is your own security review and IT scheduling.
- 1
Scoping
Review infrastructure, DICOM routing, and integration points.
- 2
Install
Provision cloud instance or deploy on-premise server. Configure DICOM.
- 3
Validate
Run test studies; confirm PACS/CVIS/EMR integration end-to-end.
- 4
Go Live
Production routing, ongoing monitoring, support. Disable any time.
Security and Compliance: Certifications, Audits and Privacy Law
GDPR & HIPAA Compliant
Patient data handled under both European Union and United States privacy law. These are legal obligations, not certifications
ISO 27001:2022 Certified
An information security management system audited by an external body
SOC 2 Type II
Security controls tested by an independent auditor over a period, not a day
MDSAP Certified
One quality-system audit accepted by regulators in the United States, Canada, Japan, Brazil and Australia
Frequently Asked Questions
Quick answers to what buyers and clinicians ask first. For deeper product detail, see the platform overview.
What does Us2.ai do?
Us2.ai is an FDA-cleared AI platform that fully automates echocardiogram analysis: measurements, guideline-based conclusions, and a structured draft report, typically within two minutes of a single DICOM upload. It plugs into existing PACS, CVIS, and reporting systems without changing how studies are acquired.
How is Us2.ai different from other AI echocardiography tools?
Three differences a buyer can verify. Breadth of report: cardiac amyloidosis, heart failure, aortic stenosis and pulmonary hypertension are assessed in the same pass that produces the report, and for cardiac amyloidosis the Us2.ca deep-learning model runs inside the same automated, guideline-based measurement and report. Depth of evidence: the results are published in peer-reviewed journals and indexed here paper by paper, rather than summarized. Independence: it is vendor-neutral across GE, Philips, Siemens, Canon and handheld POCUS, and deploys cloud or on-premise.
Is echocardiography the same as cardiac ultrasound?
Yes. Echocardiography is ultrasound imaging of the heart, and an echocardiogram is a cardiac ultrasound scan. Us2.ai brings AI to cardiac ultrasound (echocardiography) specifically: it reads standard echo loops and generates a full structured draft report, typically within two minutes. Its FDA and CE clearances cover echocardiography, not general-purpose ultrasound of other organs.
Where is Us2.ai cleared for clinical use?
Us2.ai is cleared, registered or available in 33 regulatory markets, including FDA (United States), CE MDR (European Union), MHRA (United Kingdom), TGA (Australia), Health Canada, PMDA (Japan), and HSA (Singapore). See Regulatory Status for the full market-by-market list with certificate identifiers.
How long does it take to deploy Us2.ai?
Both paths run the same four milestones: scoping, install, clinical validation, and production. Cloud needs no hardware procurement, so the four can run back to back; on-premise waits for your server. Much of the elapsed time on either path is your own security review and IT scheduling rather than our work. See Deployment & Security for the full implementation playbook.
Is AI echocardiography reimbursable?
In the United States, echocardiography procedures are billed under established Category I CPT codes (e.g. 93306 for complete TTE, 93350 for stress echo). The study is billed as it normally would be, and the physician interpretation that Us2.ai augments is reported under the professional component. The HFpEF analysis in Us2.v2 meets the CPT Category III 0932T code descriptor, so hospitals and physicians who use it can report 0932T. The provider decides what to code, and payment depends on the payer. See US Reimbursement for codes, Medicare payment methodologies, and OPPS / NTAP detail. Per-country coding and coverage for 12 other markets plus a 9-market bundle is available under Reimbursement worldwide.
How accurate is Us2.ai?
Us2.ai's automated measurements have been validated in peer-reviewed studies against expert readers, with agreement at or above inter-reader variability for ejection fraction, GLS, diastolic function, and disease detection endpoints. See Clinical Evidence for the full publication record.
Is patient data safe with Us2.ai?
Us2.ai is HIPAA and GDPR compliant, ISO 27001:2022 certified, SOC 2 Type II audited, and MDSAP certified. Cloud studies and reports stay in the one AWS region each site is set up in. On-premise deployment is available where data must remain inside the hospital network.
Book a Demo
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Prefer to try it on your own studies first? Request a free 30-day trial. What a trial needs from you: participant names for logins, a baseline to compare against, and a decision date.