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Intellectual Property

AI Echocardiography Patent Portfolio

Us2.ai holds eight issued US patents on AI echocardiography, protecting the automated analysis workflow end to end: image recognition, cardiac measurement, acquisition guidance, and disease detection. Counterpart grants and approvals extend that protection internationally.

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8
Issued US patents
5
Additional jurisdictions
2018
Earliest priority filing
United States

Issued US Patents

Each patent below is issued by the United States Patent and Trademark Office (USPTO) and links to its public record. Patents are issued to Eko AI Pte Ltd, the Singapore-registered entity operating as Us2.ai.

Foundation: Automated Echo Analysis

The core patent family protecting fully automated recognition and analysis of echocardiogram images, without manual measurement.

Patent
Issued
What It Covers
Patent US 10,631,828 B1
Issued Apr 28, 2020
What It Covers Automated AI-based clinical workflow that recognizes and analyzes both 2D and Doppler modality echocardiogram images to produce automated cardiac measurements for the diagnosis, prediction, and prognosis of heart disease.
Patent US 10,702,247 B2
Issued Jul 7, 2020
What It Covers Use of multiple AI neural networks in an automated clinical workflow that recognizes and analyzes 2D and Doppler modality echocardiogram images for automated cardiac measurements and the diagnosis, prediction, and prognosis of heart disease.
Patent US 11,301,996 B2
Issued Apr 12, 2022
What It Covers Federated-learning-based training of the neural networks in an automated clinical workflow that recognizes and analyzes 2D and Doppler modality echocardiogram images.
Patent US 11,446,009 B2
Issued Sep 20, 2022
What It Covers Clinical workflow to diagnose heart disease based on cardiac biomarker measurements combined with AI recognition of 2D and Doppler modality echocardiogram images.

Image Acquisition and Point of Care

Extending automated analysis upstream to the ultrasound device itself: image capture guidance and mobile point-of-care scanning.

Patent
Issued
What It Covers
Patent US 11,931,207 B2
Issued Mar 19, 2024
What It Covers Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device.
Patent US 12,001,939 B2
Issued Jun 4, 2024
What It Covers Artificial intelligence (AI) based guidance for an ultrasound device to improve capture of echo image views.

Disease Detection and Severity Grading

Automated detection and grading of specific cardiac conditions from the same 2D and Doppler echo analysis pipeline.

Patent
Issued
What It Covers
Patent US 12,322,100 B2
Issued Jun 3, 2025
What It Covers Automated clinical workflow that recognizes and analyzes 2D and Doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity. See it in the product: Aortic Stenosis
Patent US 12,400,762 B2
Issued Aug 26, 2025
What It Covers Automated clinical workflow that recognizes and analyzes 2D and Doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy. See it in the product: Cardiac Amyloidosis

Patent marking notice. This page is provided to satisfy the virtual patent marking provisions of 35 U.S.C. § 287(a). Us2.ai's automated echocardiography analysis software is protected by one or more of the United States patents listed above and by their international counterparts. Additional patent applications may be pending in the United States and other jurisdictions.

International

Protection Beyond the United States

The core patent family extends internationally through the Patent Cooperation Treaty application PCT/IB2018/001591, with counterpart patents granted or approved in five additional jurisdictions.

China
CNIPA
Granted
ZL 201880100205.3
Europe
EPO
Approved
—
Japan
JPO
Granted
JP 7290231 B2
Singapore
IPOS
Granted
11202105378Q
Canada
CIPO
Approved
—

Patent protection is distinct from regulatory clearance. For market-by-market device clearances and registrations, see Regulatory Status by Market.

FAQ

Common Patent Questions

For licensing, partnership, or IP questions not covered here, contact us.

Is Us2.ai's technology patented?
Yes. Us2.ai holds eight issued US patents covering its automated AI echocardiography workflow, from image recognition and automated cardiac measurements to acquisition guidance and disease detection. Counterpart patents of the core family are granted in China, Japan, and Singapore and approved in Europe and Canada.
How many patents does Us2.ai hold?
Eight issued US patents, plus international counterparts of the core patent family: granted in China (ZL 201880100205.3), Japan (JP 7290231 B2), and Singapore (11202105378Q), and approved in Europe and Canada.
Why do the patent records list Eko AI Pte Ltd as the assignee?
Eko AI Pte Ltd is the Singapore-registered legal entity that operates as Us2.ai. Public patent records at the USPTO and other patent offices carry the legal entity name, so patents assigned to Eko AI Pte Ltd are Us2.ai patents.
What do Us2.ai's patents cover?
The portfolio protects the automated clinical workflow end to end: AI recognition and analysis of 2D and Doppler modality echocardiogram images, automated cardiac measurements, federated learning for training the neural networks, diagnosis combining cardiac biomarkers with echo analysis, AI-based image capture guidance on ultrasound devices including mobile point-of-care scanners, and automated detection and severity grading of aortic stenosis, cardiac amyloidosis, and hypertrophic cardiomyopathy.
Are patents the same as regulatory clearance?
No. Patents protect the technology as intellectual property, while regulatory clearance (FDA 510(k), CE marking under EU MDR, MHRA registration) is what authorizes clinical use in a given market. Us2.ai holds both: eight issued US patents and regulatory clearances in 28+ markets. See the Regulatory Status by Market page for clearances by country.
Related

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Regulatory Status

FDA, CE, MHRA, and 28+ market clearances with certificate numbers.

Clinical Evidence

150+ peer-reviewed studies validating accuracy, reproducibility, and outcomes.

Platform Overview

The patented automated workflow in production: from DICOM in to report out.

Our Story

The founding team and research origin behind the patented technology.

The science is peer-reviewed. The technology is patented.

See the Patented Workflow in Action

Eight issued US patents protect the automation your lab would run on. Book a demo to see automated measurements, detection, and reporting on your own studies, or contact us about licensing and partnerships.

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