Automated Echo Analysis & Reporting Software
Fully automated, editable echo reports with guideline-based conclusions for the clinician to review. From image to report in zero clicks.
Why Choose Us2.ai?
Purpose-built AI for automated analysis of standard DICOM echocardiograms.
Fully Automated
From image to report in zero clicks. FDA-cleared parameters measured automatically. No frame selection, no manual annotation required.
Guideline-Based Conclusions
Guideline-based conclusions for heart failure, aortic stenosis, and pulmonary hypertension from automated measurement, plus the FDA-cleared Us2.ca module that flags studies suggestive of cardiac amyloidosis.
Guideline-Adherent & Explainable
Measurements follow international guidelines, with transparent AI annotations. Every result is traceable and fully editable by the clinician.
Connect Anywhere
Compatible with GE, Philips, Siemens, Canon, and handheld POCUS devices. Cloud or on-premise, integrating with PACS, CVIS, or EMR.
What Every Report Contains
The labeled measurement list and main findings from the User Guide Us2.v2, US edition, Rev M, word for word. The clinician can edit any measurement or suggested conclusion before signing off.
45 measurements
Left ventricular size and function (8)
- LVEF MOD Biplane Left Ventricular Ejection Fraction calculation based on Method of Disks
- LVEDV MOD Biplane Left Ventricular End Diastolic Volume biplane calculation based on Method Of Disks
- LVESV MOD Biplane Left Ventricular End Systolic Volume biplane calculation based on Method Of Disks
- LVSV MOD Biplane Left Ventricular Stroke Volume biplane calculation based on Method Of Disks
- LVIDd Left Ventricular Internal Diameter at end diastole
- LVIDs Left Ventricular Internal Diameter at end systole
- LVPWd Left Ventricular Posterior Wall thickness at end diastole
- IVSd Inter Ventricular Septal thickness at end diastole
Atria (2)
- LAESV MOD Biplane Left Atrial End Systolic Volume biplane calculation based on Method Of Disks
- RA Area Right Atrial area at end systole
Right ventricle (5)
- RVIDd Right Ventricular Internal Diameter at end diastole
- TAPSE Tricuspid annular plane systolic excursion
- RV E ‘ Early diastole tissue velocity taken from right ventricular free wall
- RV A’ Late diastole tissue velocity taken from right ventricular free wall
- RV S’ Systolic tissue velocity taken from right ventricular free wall
Diastolic function: tissue and mitral Doppler (11)
- PWTDI lateral e’ Early diastolic tissue velocity taken from the lateral wall of LV
- PWTDI lateral a’ Late diastolic tissue velocity taken from the lateral wall of LV
- PWTDI lateral s’ Systolic tissue velocity taken from the lateral wall of LV
- PWTDI septal e’ Early diastolic tissue velocity taken from the septal wall of LV
- PWTDI septal a’ Late diastolic tissue velocity taken from the septal wall of LV
- PWTDI septal s’ Systolic tissue velocity taken from the septal wall of LV
- PWMV E Pulse wave velocity of early diastolic transmitral flow
- PWMV A Pulse wave velocity of late diastolic transmitral flow
- PWMV DecT Deceleration Time of early diastolic MV transmitral flow
- PWMV ADur Late diastolic transmitral flow
- E/e’ mean E/e’ mean
Pulmonary pressure (1)
- CW TrV Vmax Continuous wave of tricuspid regurgitation maximum velocity
Strain (5)
- LV GLS Left ventricular global longitudinal strain
- A4C LV GLS Left ventricular global longitudinal strain in A4C
- A3C LV GLS Left ventricular global longitudinal strain in A3C
- A2C LV GLS Left ventricular global longitudinal strain in A2C
- LV Regional Strain LV Regional Strain
Aortic root, outflow tract and aortic valve (13)
- Sinotubular Junction Sinotubular Junction diameter
- Sinus valsalva Sinus of valsalva diameter
- LVOT Diameter Left ventricular outflow tract diameter
- CW AoV Vmax Continuous wave aortic valve maximum velocity
- CW AoV VTI Continuous wave aortic valve velocity time integral
- CW AoV Pmax Continuous wave aortic valve maximum pressure
- CW AoV Pmean Continuous wave aortic valve mean pressure
- PW LVOT Vmax Pulse wave left ventricular outflow tract maximum velocity
- PW LVOT VTI Pulse wave left ventricular outflow tract velocity time integral
- PW LVOT Pmax Pulse wave left ventricular outflow tract maximum pressure
- PW LVOT Pmean Pulse wave left ventricular outflow tract mean pressure
- AVA Aortic valve area
- VR Velocity ratio
Main findings, from international guidelines
- LV Systolic Function
- LV Diastolic Function
- LV Size
- LV Geometry
- RV Function
- RV Size
- LA Size
- RA Size
- Heart Failure with Preserved Ejection Fraction (HFpEF)
- Heart Failure with mildly reduced Ejection Fraction (HFmrEF)
- Heart Failure with reduced Ejection Fraction (HFrEF)
- Mild Aortic Stenosis
- Moderate Aortic Stenosis
- Severe Aortic Stenosis
- Low Echocardiographic Probability of Pulmonary Hypertension
- Intermediate Echocardiographic Probability of Pulmonary Hypertension
- High Echocardiographic Probability of Pulmonary Hypertension
- Cardiac Amyloidosis
A finding is shown only when every measurement its guideline needs is available. Measurements outside guideline ranges are highlighted for review. These are report conclusions for the clinician, not separate diagnostic indications; see what each market's labeling includes.
How Us2.ai Fits Into Your Workflow
No workflow disruption. Us2.ai slots into your existing infrastructure and processes studies automatically.
Device
AI Engine
/ EMR
Vendor-neutral DICOM from GE, Philips, Siemens, Canon, and handheld POCUS devices. Standard DICOM routing via your existing DICOM router.
Cloud or on-premise deployment. Automated view classification, measurement, and guideline-based report conclusions. No manual intervention.
Structured reports delivered back to PACS, CVIS, or EMR. HL7 and DICOM SR supported. Results available before the patient leaves.
What Stays the Same When You Deploy Us2.ai
What stays the same on your side when you deploy Us2.ai, and what each point depends on.
- Same scanning protocol
- Sonographers scan as they do today. Us2.ai reads the views of a standard transthoracic protocol, so no new views or steps are added.
- Results in the systems you already read in
- Reports return to your PACS, CVIS or EMR as DICOM-SR, HL7 or PDF.
- Same reporting responsibility
- The cardiologist retains final sign-off. Us2.ai provides a pre-populated draft, and clinical authority stays with the physician.
- Vendor-neutral
- Works with GE, Philips, Siemens, Canon, and handheld POCUS devices.
- Reversible
- Routing to Us2.ai can be switched off at any time, and reports already delivered stay in your PACS.
- Standard DICOM routing
- Integration uses DICOM routing your IT team already runs, configured with settings we provide. HL7 and FHIR are available where needed.
Use of Us2.ai Along The Disease
Management Pathway
Where Us2.ai fits in cardiac care, from referral to diagnosis to follow-up.
POCUS device connected to the Us2.ai software
Trained sonographers and other licensed healthcare professionals
Standardized echo reporting for your clinical routine
Connect echo carts, CVIS, EMR, PACS or POCUS to Us2.ai software (Cloud or on-premise)
Longitudinal surveillance and PACS-based case finding at scale
Connect echo carts, CVIS, EMR, PACS or POCUS to Us2.ai software (Cloud or on-premise)
The Shift to Automated Structured Reporting
Three ways an echo report gets produced, each defined by what the software does. This is not a comparison with named products. Ask any vendor, including us, which of these its product does.
Manual Reporting
- Manual frame selection
- Reader-dependent variability
- Minutes per report
- Report backlogs
- Specialist-dependent throughput
Measurement-Assist Reporting
- Software suggests individual measurements
- Less tracing than a manual read
- Each measurement approved click by click
- The reader applies the guidelines and writes the conclusions
Automated Structured Reporting
- Zero-click analysis
- Less variability than between expert readers (Tromp et al., Nature Communications 2022)
- A draft report typically within two minutes
- Guideline-based conclusions in every report
- Fully editable. Physician retains final sign-off
Frequently Asked Questions
Common questions about the Us2.ai platform.
What is AI echocardiography?
AI echocardiography, also called AI cardiac ultrasound, uses artificial intelligence to automatically analyze echocardiogram (cardiac ultrasound) images, performing measurements and generating structured reports. Us2.ai's platform analyzes a study with zero clicks, from DICOM to a report with guideline-based conclusions for the clinician to review.
Is AI echocardiography the same as AI cardiac ultrasound?
Yes. Echocardiography is ultrasound imaging of the heart, so AI echocardiography and AI cardiac ultrasound describe the same thing: artificial intelligence applied to cardiac ultrasound studies. Us2.ai is FDA-cleared and CE-marked for echocardiography specifically, not general-purpose ultrasound of other organs such as abdominal, obstetric, or vascular imaging.
Is Us2.ai FDA cleared?
Yes. Us2.v1 and Us2.v2 are FDA 510(k) cleared for automated echocardiographic measurement, and the Us2.ca cardiac amyloidosis module is cleared separately. Us2.ai is also CE marked (Class IIb) and is cleared, registered or available in 34 regulatory markets, including the United States, European Union, Canada, Australia, Singapore and Japan.
Which conditions does the Us2.ai report assess?
The report adds guideline-based conclusions for heart failure (including HFpEF), aortic stenosis, and the echocardiographic probability of pulmonary hypertension, computed from its automated measurements for the clinician to review. The separately cleared Us2.ca module flags studies suggestive of cardiac amyloidosis in adults with increased wall thickness.
Which ultrasound machines does Us2.ai work with?
Us2.ai is vendor-neutral. It reads standard DICOM from GE, Philips, Siemens, Canon, and handheld POCUS devices, and integrates with PACS, CVIS, or EMR through standard DICOM routing, with cloud or on-premise deployment options.
How much time does AI echocardiography save?
In one peer-reviewed study of 23 patients (Hirata et al., J Echocardiogr 2024), combined measurement and report creation time fell by 70%. In a randomized trial of 585 patients (JAHA 2026), sonographers completed two more exams per day. At Endeavor Health, studies done with Us2.ai took 35.0% less time across 47 studies (J Am Soc Echocardiogr 2026).
Learn More About Us2.ai
Get the full overview of features, workflow integration, and clinical capabilities in our product brochure.
Us2.ai Product Brochure
Inside:
- Regulatory clearances and indications for use
- Main findings, disease detection and the automated measurements per edition
- Product workflow, processing steps and report structure
- Use cases along the disease management pathway
Regulatory Clearances Worldwide
We're continually working to bring regulatory approvals to your region.
United States 
Europe 
Canada 
Australia 
New Zealand 
Singapore 
Indonesia 
Thailand 
Taiwan 
Vietnam 
India 
Israel 
Mexico 
Brazil 
Philippines 
United Kingdom 
Japan 
Hong Kong 
Malaysia United States Europe Canada Australia New Zealand Singapore Indonesia Thailand Taiwan Vietnam India Israel Mexico Brazil Philippines United Kingdom Japan Hong Kong Malaysia Performance validated across multiple vendor systems, multi-center studies and diverse patient populations. FDA cleared, CE marked, and cleared, registered or available in 34 regulatory markets. The automated workflow itself is protected by eight issued US patents.
What Was Tested, on Whom, and the Result
Each capability with its study, population, comparison, result, and the limit to know before relying on it. Research results describe the study, not a cleared indication.
See Us2.ai in Action
Fully automated echocardiographic analysis. Book a demo to see how it works.
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